Jun 3, 2004 (CIDRAP News) The General Accounting Office (GAO) has urged federal agencies to step up their efforts to determine if the use of certain antibiotics in animals endangers human health by making bacteria resistant to those antibiotics. However, the GAO said, the approved drugs reviewed so far are not the ones the FDA considers critically important to human health, and the reviews have taken at least 2 years to complete. “Therefore it may be some time before FDA completes its reviews of critically important drugs in order to determine if enforcement action to protect human health is warranted,” the report says. The agency recommends that the FDA accelerate its reviews of antibiotics that are used in animals and are important for human health. GAO report “Antibiotic Resistance: Federal Agencies Need to Better Focus Efforts to Address Risk to Humans from Antibiotic Use in Animals”http://www.gao.gov/new.items/d04490.pdf The report also notes that the FDA has moved to bar the use of the fluoroquinoline antibiotic enrofloxacin in poultry because of evidence that fluoroquinoline use in animals has caused the transfer of resistant pathogens to humans. However, the drug has remained on the market the past 3 years because the manufacturer has challenged the FDA move. Concerning the need for data, the GAO says federal agencies have expanded their research on antibiotic resistance related to antibiotic use in animals, but it is too early to judge the effectiveness of their efforts to reduce the risk to human health. The FDA, CDC, and USDA have increased their surveillance and research on antibiotic resistance in animals and humans in recent years. The GAO, Congress’s investigative arm, spent a year preparing the report. It was requested by three senatorsOlympia J. Snowe, R-Me.; Tom Harkin, D-Iowa; and Edward M. Kennedy, D-Mass. In addition, the GAO said research on the human health risk is crippled by a lack of data on the types and amounts of antibiotics used in animals. The agency recommended that the US Department of Agriculture (USDA) and the Department of Health and Human Services (HHS) work together to collect the needed information. The USDA and HHS, on reviewing a draft of the GAO report, generally agreed with it, the GAO says. HHS officials said that pharmaceutical companies have the most useful data on antibiotic use in animals. Current regulations would have to be revised to put the data that companies have to report to the FDA in a more useful format for research on antibiotic resistance, the officials said. Mar 18, 2004, CIDRAP News story, “FDA closer to banning enrofloxacin use in poultry” In a report released last week, the GAO said the Food and Drug Administration (FDA) should speed up its risk assessments to determine whether it should restrict the use in animals of antibiotics considered critically important to human health. “Although they have made some progress in monitoring antibiotic resistance, federal agencies do not collect the critical data on antibiotic use in animals that they need to support research on the human health risk,” the report states. In Denmark, collection of detailed data on antibiotics given to animals has enabled scientists to trace the effects on resistant bacteria in humans and to devise strategies to minimize the health risks, the GAO says. The agency recommends that the FDA and USDA together develop and implement a plan to collect the needed data. The report acknowledges that this will cost money but says it should not be excessively expensive, because existing FDA and USDA programs can provide a framework that can be expanded to begin gathering the information. However, the FDA “is not collecting data on antibiotic use in animals, and USDA’s data collection activities are limited to a few swine farms,” the report says. It suggests that the agencies gather information on the types and quantities of antibiotics sold for animals, the purpose of their use (disease treatment or growth promotion), and the species in which they are used. Many studies suggest that the use of antibiotics in animals poses risks to human health, but a few studies indicate that the health risks are minimal, the report says. The document notes that the FDA has laid out a “risk assessment framework” determining the human health risks. The agency is using the framework in reviewing both currently approved animal antibiotics and manufacturers’ applications for approval of new ones. See also: The United States differs from some of its key trading partners in the use of antibiotics in food animals, the report notes. While the United States and Canada allow some drugs that are important in human medicine to be used for growth promotion, the European Union and New Zealand have banned this practice. In addition, the EU plans to ban the use of any antibiotic for growth promotion by 2006. These policy differences have not significantly affected US meat exports so far, but that could change, the report says. The agency concluded that antibiotic-resistant bacteria have been transferred from animals to humans and that this transfer appears to pose significant risks to human health. Some studies have produced evidence of links between changes in antibiotic use in animals and bacterial resistance to antibiotics in humans. Further, genetic studies of bacteria have established that antibiotic-resistant Campylobacter and Salmonella are transferred from animals to humans, the report says.
— Aaron Gordon scored 25 points and Markelle Fultz added 21 as the Orlando Magic rallied to beat the Detroit Pistons 116-112 in overtime. Gordon, who also had nine rebounds and nine assists, hit consecutive 3-point shots late in the fourth quarter to help Orlando erase a seven-point deficit. Christian Wood had 26 points and 12 rebounds for the Pistons, who rallied from a 22-point deficit but lost for the 11th time in 13 games.NBA-NEWSMavs’ Doncic returns after missing 7 games with ankle sprainDALLAS (AP) — Luka Doncic is back for the Dallas Mavericks after missing seven games with a sprained right ankle. The first-time All-Star played in the final game before the break against Sacramento. Doncic injured the same ankle and missed four games earlier this season before spraining the ankle again in practice. The 20-year-old sensation is an All-Star starter in his second season. Doncic also is planning to play in the futures game during All-Star weekend in Chicago.KOBE BRYANT-BURIAL February 12, 2020 NFL-NEWSBrowns’ Garrett reinstated by NFL after 6-game suspensionUNDATED (AP) — Browns star defensive end Myles Garrett has been reinstated by the NFL after being suspended for hitting Steelers quarterback Mason Rudolph in the head with a helmet in a Nov. 14 game. The 24-year-old Garrett missed Cleveland’s final six games last season after his disturbing attack on Garrett. The 2017 top overall pick met with Commissioner Roger Goodell on Monday in the final step before he could be cleared. Garrett has expressed remorse for pulling off Rudolph’s helmet and smashing him in the head with it in the final seconds of Cleveland’s nationally televised win over Pittsburgh. Kobe Bryant, daughter buried in Southern California cemeteryLOS ANGELES (AP) — Death certificates show Kobe Bryant and his daughter Gianna were buried Friday in a cemetery near the family’s Southern California home. Pacific View Memorial Park in Corona del Mar features meticulous landscaping, open courtyards and fountains. Actor John Wayne also is buried there. The Bryants and seven others were killed in a Jan. 26 helicopter crash. The cause is under investigation. The retired basketball superstar, his daughter and the other victims will be honored at a Feb. 24 public memorial at Staples Center, where Bryant starred for most of his 20-year career with the Los Angeles Lakers.The date 2/24 corresponds with the No. 24 jersey he wore and the No. 2 worn by Gianna, whose team was coached by her father.MEN’S COLLEGE T25 BASKETBALL SCHEDULEA look around the T25 Share This StoryFacebookTwitteremailPrintLinkedinRedditNBA-SCHEDULERaptors’ 15-game win streak snappedUNDATED (AP) — The Toronto Raptors had their franchise-record winning streak stopped at 15 games with a 101-91 loss to the Brooklyn Nets. The defending NBA champions were hoping to keep rolling right into the All-Star break but couldn’t find the form that helped them average 121.2 points and shoot 50% over the previous 15 games. This time, the Raptors hit only 37.8%, with Kyle Lowry’s triple-double coming on a night the All-Star point guard was just 4 for 13. Caris LeVert scored 20 points for the Nets, who ended a six-game losing streak against the Raptors. That included a loss Saturday in Toronto, where LeVert scored a career-best 37 points. Update on the latest sports NHL-NEWSBouwmeester remains hospitalizedUNDATED (AP) — St. Louis Blues defenseman Jay Bouwmeester remains hospitalized and is undergoing tests a day after suffering a cardiac episode and collapsing on the bench during a game in Anaheim. General manager Doug Armstrong says the 36-year old defenseman was unresponsive and a defibrillator was used Tuesday night. He says Bouwmeester regained consciousness immediately before being taken to an Anaheim hospital. The team stayed overnight in Southern California before taking a chartered flight to Las Vegas, where they will play the Golden Knights on Thursday.In other NHL news:— Montreal Canadiens captain Shea Weber will be out four to six weeks with a sprained left ankle. The defenseman was injured during a game in New Jersey on Feb. 4. Weber has 13 goals and 21 assists in 55 games this season UNDATED (AP) — Devon Dotson scored 15 points and No. 3 Kansas finished the game with a 9-0 run to beat 14 West Virginia 58-49. The Jayhawks won for the ninth straight time and remain a game behind first-place Baylor in the Big 12. Isaiah Moss had seven of his 13 points after halftime for Kansas. West Virginia fell flat after leading by as many as nine points in each half and lost at home for the first time this season. Oscar Tshiebwe led the Mountaineers with 14 points and nine rebounds, but he had just two points after halftime.Elsewhere in court action:— Damien Jefferson, Ty-Shon Alexander, Marcus Zegarowski and Denzel Mahoney all scored 18 points and No. 23 Creighton posted its second road win over a Top 10 team this month with an 87-82 decision over No. 10 Seton Hall on Wednesday night. Christian Bishop added 11 points as the Bluejays won for the sixth time in seven games, including a win at No. 8 Villanova at the start of the month. Quincy McKnight had 20 points to lead Seton Hall, which lost for the second time in 14 games.— Austin Wiley had 18 points, a career-high 17 rebounds and five blocked shots and No. 11 Auburn beat rival Alabama 95-91 Wednesday night in the Tigers’ latest foray into overtime. The Tigers picked up their fourth overtime win of the last five games. This time they scored the first eight points of overtime and held on for redemption from an earlier 19-point loss to the Crimson Tide. J’Von McCormick, who hit the game-winner and three big 3-pointers in an overtime win over No. 25 LSU, made two free throws with 18 seconds left.— Sean McDermott scored 14 points to lead No. 19 Butler to a 66-61 victory over Xavier. Kamar Baldwin added 11 points and Jordan Tucker scored 10 for the Bulldogs. Naji Marshall scored 20 points to lead the Musketeers. Tyrique Jones had 19 points and 10 rebounds for Xavier, his 17th double-double. Butler shot 47% and Xavier went 44% from the field. Bulldogs guard Aaron Thompson took an elbow to the head and went to the floor with Butler leading 42-25. He left the game and did not return. Associated Press — Minnesota Wild defenseman Matt Dumba has been fined $5,000 for slashing Vegas Golden Knights forward Ryan Reaves. The NHL’s Department of Player Safety announced the punishment. It’s the maximum allowable amount under the Collective Bargaining Agreement. Dumba hit Reaves with his stick in the midsection in the first period of the game on Tuesday night. The Wild beat the Golden Knights 4-0.— Winnipeg coach Paul Maurice has signed a multi-year extension with the Jets. In his seventh season as Jets coach, Maurice has guided Winnipeg to the playoffs three times, including a run to the Western Conference final in 2018.— Montreal Canadiens captain Shea Weber will be out four to six weeks with a sprained left ankle.— The NHL and NHL Players’ Association have scheduled another round of labor talks next week. One of the more pressing issues is whether the NHL elects to send players to compete in the 2022 Beijing Games after not participating in the 2018 Olympics in South Korea. The NHL remains reluctant to reverse course, despite Olympic officials providing assurances of being ready to lift various major stumbling blocks during a meeting that included NHLPA representatives.— Jeremy Roenick will not be returning to NBC Sports after his suspension for making inappropriate comments about coworkers during a podcast. A network spokesman confirmed to The Associated Press that Roenick will not be back on the air. Roenick played 20 NHL seasons with the Blackhawks, Coyotes, Flyers, Sharks and Kings before moving into television. He had been an analyst at NBC Sports since 2010. The Nets extended a 10-point lead after three quarters to 80-65 in the opening 90 seconds of the fourth and spent the rest of the game turning back every Toronto attempt to get back in it. The Raptors’ best shot came when Ibaka made a 3-pointer and VanVleet converted a three-point play to cut it to 91-82 with 4:13 remaining, but LeVert made consecutive baskets to quickly push the lead back into double figures.The Nets scored the first seven points of the second quarter to open a 30-19 lead. The Raptors had the deficit down to six in the final minute of the period, but Harris made three free throws and then a 3 to make it 52-40 at halftime.Elsewhere in hoop action:— The Indiana Pacers took advantage of a 10-0 fourth-quarter run to snap a six-game losing streak with a 118-111 victory over the Milwaukee Bucks. T.J. Warren had 35 points and Malcolm Brogdon had 17 points and 13 assists to lead the Pacers. Bucks All-Star Giannis Antetokounmpo (YAH’-nihs an-teh-toh-KOON’-poh) missed his second straight game since his girlfriend gave birth to the couple’s first child. Milwaukee still made it difficult after methodically trimming a 25-point deficit to four early in the fourth. The Pacers scored 10 straight and the Bucks couldn’t get closer than seven as their five-game winning streak ended. Donte DiVincenzo scored 19 for Milwaukee.— Tristan Thompson scored 27 points and grabbed 11 rebounds, Larry Nance Jr. had a career-high 23 points, and the Cleveland Cavaliers broke a 12-game home losing streak by defeating the Atlanta Hawks 127-105. Cleveland was coming off its worst home loss in franchise history. The Cavaliers went ahead midway through the first quarter and won at Rocket Mortgage FieldHouse for the first time since beating the Hawks on Dec. 23. Trae Young led the Hawks with 27 points and 12 assists.
Related Articles UK racing remains hopeful for crowd pilot events August 14, 2020 StumbleUpon Share Betfair has been named as the official sponsor for both the Northumberland Plate Festival and Fighting Fifth Hurdle after signing a new deal with Newcastle Racecourse and the Arena Racing Company (ARC).Listed as the feature race, the Betfair Exchange Northumberland Plate is due to be broadcast live across ITV 1 and Sky Sports Racing. Other feature races run across the three-day meeting will also include the Group 3 Betfair Exchange Chipchase Stakes and the Group 3 Betfair Exchange Hoppings Stakes.Brand Director for Betfair in Europe, Stephen Mault, commented: ‘’To add such an historic Heritage Handicap like the Northumberland Plate and the Grade One Fighting Fifth Hurdle to our ever evolving and increasing Horseracing sponsorship portfolio clearly outlines our commitment to the sport. “Our own heritage is steeped in Horseracing and we strive to give racegoers a very unique experience when they attend a Betfair sponsored race day. That is something we, in conjunction with the team at Newcastle, will be focusing on delivering in the coming weeks and months.’’ In addition to sponsoring the Northumberland Plate fixture, Betfair is also due to become the headline sponsor for the Grade One Fighting Fifth Hurdle. Run at the beginning of December over two miles, the race has been won in the last two years by two-time Champion Hurdle winner Buveur D’Air.Executive Director of Newcastle Racecourse, David Williamson, added: “We’re delighted to welcome Betfair on board as the principal partner of two of our feature meetings at Newcastle Racecourse. The Northumberland Plate is a race very much embedded in the history of the area and we look forward to a new era with such a prestigious new sponsor.”“The Fighting Fifth often attracts some of the top two-mile hurdlers from Britain and Ireland and the clash between Buveur D’Air and Samcro was one of the most anticipated clashes of last season.” Submit Flutter moves to refine merger benefits against 2020 trading realities August 27, 2020 Share ‘Deal maker’ Rafi Ashkenazi ends Flutter tenure August 27, 2020