It’s surprisingly snowing quite hard in Fort Worth, Texas, this afternoon. TCU running back Aaron Green is using the rare snowfall to channel one of his favorite athletes – LeBron James. Standing on the Horned Frogs’ campus, Green did the Cleveland Cavaliers’ star’s famed pre-game powder toss, using a snowball in place of the chalk. Check it out: Well done, Aaron. TCU opens its season Sept. 3 against Minnesota in Minneapolis.
American TweetPenn State made some news yesterday when it was revealed that the team literally buried the game tape of its 27-10 season-opening loss to Temple with a shovel. In the embarrassing defeat, the Nittany Lions surrendered 10 sacks. While Penn State was ready to let that game go, the American Athletic Conference, of which Temple is a member, wants to relish the memory of it . That’s why the AAC’s official football Twitter account dropped a solid troll job on Penn State this morning. Penn State may have buried the game tape, but you can watch all 10 @Temple_FB sacks from Sat on our YouTube page https://t.co/xkp5lidkzS— American Football (@American_FB) September 9, 2015That’s tremendous. This was Temple’s first win over PSU in over 70 years, and they set a conference sack record in the process. The AAC doesn’t have many opportunities to brag about its football accomplishments, so it is understandably proud of the Owls’ performance.
Amber BernardAPTN NewsThe Senate committee on Aboriginal Peoples has released a report on the history between Indigenous people and Canada.The vision of the committee in releasing How did We Get Here?, was to implement parts of the study into the classroom.“So we imagined for instance an audience of high school kids, who may not know a whole lot of Indigenous people, who may be able to pick up this kind of report find it interesting,” said Senator Daniel Christmas.The study looks at an unvarnished account of the development of Canada, to treaties and polices that have affected Indigenous communities.Melissa Campbell Schwartz, department head of First Nations, Metis and Inuit studies at Hillcrest High School, picked up the report for her grade 11 Indigenous Literature course.“The senate report is exciting,” Schwartz told APTN News.“It gives us another piece to move the steps forward.”Schwartz believes educators play a big role in shifting the conversation to include Indigenous perspectives.“As a settler within a colonial structure, I play a really interesting role, trying to change the conversation and trying to get kids to understand their role as a settler.”She says Indigenous history needs to be taught in order to create a better future between Indigenous people and Canadians.The grade 11 Indigenous literature class often starts with a discussion circle, exploring various topics affecting Indigenous people in Canada.Schwartz says her students eagerly participate in the conversation and are passionate about creating a better relationship with Indigenous people.She says some of her students after taking the class begin to challenge negative stereotypes they hear at home and in school.“They see the injustice, they see a simple answer and they want that to happen,” she said.“They become agents for change.”Students enrolled in the Indigenous literature class would like for more Canadians to learn about Indigenous history in Canada.“I think if everyone had this knowledge at a young age, there wouldn’t be any adults like there were in first contact,” said Azan Mubasher, a grade 11 student at Hillcrest High School.Students are hopeful with the Indigenous history they’ve been learning about in Schwartz class.“Knowledge is key and right now we’re taught an in depth knowledge of Aboriginal history, that personally I never knew of,” Bassant Mohamed said. “It’s definitely going to shift dynamics.”Schwartz hopes the Senate report can be used widely by educators in Canada and is confident her students will create positive change.“When I was reading it (the senate report,) I actually wrote a note to myself that Murray Sinclair had said a couple years ago about education getting us into this problem and education is what’s going to get us out,” she said.“Because I see the education getting us out.”firstname.lastname@example.org
The BCUC also received more than 70 letters of comment from members of the public and interested parties as well as three reports prepared by two independent consultants, shares the BCUC.The process also included four days of Oral Workshops for the Panel to ask Interveners questions, and for Interveners to ask questions on the independent reports.The Panel has recommended a one-month comment period on the Report to provide the Inquiry’s participants with an opportunity to submit additional evidence relevant to questions posed by the BC Government.To review the Panel’s detailed findings, refer to the Executive Summary or Final Report; CLICK HEREThe BCUC shares a final copy of the report has been provided to the Honourable Minister of Jobs, Trade and Technology. VANCOUVER, B.C. – The British Columbia Utilities Commission (BCUC) issued its Final Report with responses to questions posed by the Provincial Government and its key findings from its Inquiry into Gasoline and Diesel Prices in BC.Following the inquiry process, some of the Panel’s key findings include;There is a significant unexplained difference of approximately 13 cents per litre in wholesale gasoline prices between Southern BC and its Pacific Northwest cost comparator;The wholesale market for gasoline in BC is not truly competitive with high market concentration levels, high barriers to entry, and their ability to influence prices. Retail market prices can also be controlled by five refiner-marketers;There is no evidence to suggest that there is collusion among the retail operators nor is there evidence of cartel behaviour; andRegulation could potentially reduce the wholesale and/or retail margins to what is earned in comparable jurisdictions and reduce price volatility. However, further investigation should be done to determine if such an approach would be of benefit to British Columbian consumers.According to the BCUC, they established an independent, transparent and public inquiry process. The Panel considered evidence filed by 11 registered interveners including all major companies that have refining and retail business in BC.
Casablanca- Today, you can find anything exposed for sale on the internet—even a girl’s virginity! Catarina Migliorini, the Brazilian college girl who stirred a polemic by auctioning off her virginity online 15 months ago, is now doing it again after the initial deal proved to be a total failure. Surprisingly, someone has even proposed to her!We all remember the 21-year-old Migliorini who had sold her virginity online for $ 780,000. Well, the Japanese billionaire who won the online bid against three other bidders seemingly changed his mind, and Migliorini said she was the victim of a well-sewed dupery, especially after she shot the Justin-Sisely-made documentary “Virgins Wanted” on that very auction.The controversial Brazilian college student re-launched the online auction again, and this time on her own website, VirginsWanted2.com. Since then, one of the most tempting offers she has received for her virginity is $440,000. However, Migliorini is now raising the bar higher after she has recently received a $1.5 million marriage proposal from an undisclosed Arab billionaire. Hence, she has disregarded the $440, 000 offer, extended the deadline for bids until February 14 and started probing the very tempting marriage offer.“”I decided to continue because I received a proposal from an Arab millionaire and I’m thinking about it, [because] this proposal involves a possible marriage,” she was quoted as saying by The Huffington Post.” I decided to extend the time so I could analyze everything well in advance.”Migliorini seemed very optimistic about the Arab billionaire’s recent offer, describing the Arab proposer as a “romantic,” “handsome” and “very intelligent” man, who “lives in a beautiful mansion [and] speaks 11 languages.”Migliorini claims that she plans to donate 90% of the auction money for charity, mainly to enable certain associations in the Brazilian state of Santa Catarina, where she’s from, to build homes for people in need.However, according to Huffington Post, Australian filmmaker Sisely said he was surprised to hear Migliorini speak about the 90% charity donation part, since she had affirmed to him that offering her virginity for sale was “a business decision for her.”© Morocco World News. All Rights Reserved. This material may not be published, rewritten or redistributed
Within 20 days of the its first game, the Ohio State women’s hockey team has hired former Minnesota Golden Gophers assistant coach Nadine Muzerall as its head coach, announced in the second quarter of the Ohio State football game on Saturday.Muzerall fills a hole left by former coach Jenny Potter who left the program on Aug. 18, just five weeks before the first game and five days before classes began. OSU was 10-25-1 under Potter in 2015-16.“We’ve all heard such good things (about Muzerall),” junior defenseman Dani Sadek said. “She has a winning mindset and I think that’s what this program needs.”The first thing to know about the new Buckeye coach is her connection to the Golden Gophers’ women’s hockey program.Muzerall was on the bench of last year’s Minnesota squad that won the national championship over Boston College. She spent the past five seasons at Minnesota coaching in five national championship games and claiming four championship rings.As a player at Minnesota from 1997-2001, she began her extensive trophy case by collecting two All-American honors in 1998 and 2000. Muzerall was also on the Gophers team that won an AWCHA national championship — women’s hockey was not an NCAA-sanctioned sport until 2000-2001 season — and a 2001 Western Collegiate Hockey Association conference championship.Muzerall still holds the all-time goals record for Minnesota women’s hockey with 139 career goals. She also leads the all-time goals per game mark with 1.08. She ranks third all-time in career points with 235.The Ontario, Canada, native was the first women’s hockey player inducted into the hall of fame at the university. She is still the youngest athlete to be inducted into Minnesota’s hall of fame.Muzerall is OSU’s third coach in as many years following Porter’s departure and the resignation of former coach Nate Handrahan amidst sexual harassment allegations.OSU opens the season on Friday, Sept. 30, at Rensselaer Polytechnic Institute.
The Ohio State women’s volleyball team’s run in the NCAA tournament was cut short by a devastating loss Saturday night. The NCAA Tournament began Friday night when the Buckeyes faced Cincinnati in the first round. Behind a team-high 17.5 points from junior Katie Dull, the Buckeyes defeated Cincinnati 3-1 to advance to the second round. In the first set, two kills from freshman Emily Danks and two ace serves from junior Susan Halverson brought the Buckeyes out of a 16-12 deficit. Two Dull kills sealed the first game 25-20 for the Buckeyes.The second game had quite a different rhythm as the Buckeyes fell 25-16. The Buckeyes felt the pressure and came back in the third 25-15 and a Dull kill in the fourth ended the game 25-23 and the match 3-1. The victory was short-lived as the team was focused on its next task, No. 9 California, who defeated Lipscomb earlier in the night. Both coach Geoff Carlston and Dull were excited to get the opportunity to play California on Saturday. “First of all, I thought it was a great match,” Carlston said. “You are going crazy through it but in the end, to be able to win a match like that against a great team is neat.”Excitement immediately turned to focus.The Buckeyes met California in St. John Arena on Saturday night. The Buckeyes were slow to start in the first and trailed the entire game, falling 25-13. Seniors Ashley Hughes and Kristen Dozier exploded in the second game, opening a run early. Ohio State edged California 25-18, and tied the match 1-1.The third game was nothing short of a nail-biter. With 13 ties and four lead changes, the Buckeyes battle ended just short, 25-23. California held the lead throughout the fourth game. The Buckeyes only trailed by as many as eight points in the game, but fought back to stay within three points.The Buckeyes fell 25-20 in the fourth and 3-1 in the match. Carlston credited the players for their success just as much as the players credited the coaching staff for believing in them. “We knew we had a good team and we had something to prove,” Carlston said. “More than that, the coaching staff believed in us so every day. We came in determined to do something good with this season.”Good is an understatement. The Buckeyes finished last season 15-20 overall. This season they finished 25-11 overall and received an at-large berth to the NCAA tournament. The Buckeyes will have to say goodbye to three seniors this year, Kristen Dozier, Ashley Hughes, and Chelsea Noble. The team recognizes them for all they have given to the season and the program as they look to the future. “This year was our year to prove to the Big Ten that we are back on track and we are who we are,” sophomore Kelli Barhorst said. “We are Ohio State. We are looking forward to building on it next year.”
Even after making 10 signings this summer, Rangers boss Steven Gerrard wants “a few” more players, saying “this will be a different team from last year”.The coach say he wants to sign another centre-half during this transfer window to bolster his team’s defence, although he had already signed Connor Goldson from Brighton and Nikola Katic from Croatian side Slaven Belupo.Rangers have had a bid of £200k rejected for Hearts striker Kyle Lafferty, however, Gerrard has refused to be drawn on their interest in the player.“We have tried to add players who are hungry, the idea was to have two quality players in each position,” said Gerrard, according to Sky Sports.Owen reveals why Liverpool didn’t offer Gerrard a new contract Manuel R. Medina – September 6, 2019 According to Owen, the Reds wanted to sell Gerrard two years before he left the club and that’s why they didn’t offer him a contract renewal.“It’s no secret we are still looking to add a few pieces to the jigsaw. This will be a different team from last year.“I can’t speak on last season but the mentality of my players will be there and we will have winners on the pitch and winners on the bench.“We don’t just want numbers, we want quality. We know our targets and who we will go after.”
Iran and Iraq tied 0-0 in Matchday 3 of the 2019 AFC Asian Cup, and the Iranian team is now ready for the next stage of the competition.Iran and Iraq tied 0-0 today as the Iranian team ended up on the first place of Group D in the 2019 AFC Asian Cup.And Iran coach Carlos Queiroz has said that the real competition starts now.“I have no energy now. It was so intense, but it was played in good spirits. There was a lot of excitement in both teams,” Queiroz told The Khaleej Times.“We controlled the game. In the first half, we played better. We created two chances. The second half, it was 50-50. At the end of the day, for the commitment and the effort from both teams, I think the draw was a fair result.”Ali Daei wouldn’t be upset if Ronaldo breaks his scoring record Andrew Smyth – September 13, 2019 Iranian legend Ali Daei wouldn’t be upset to lose his record as international football’s all-time record scorer to the “great” Cristiano Ronaldo.“We played a very good game against a very tough team. My players came out with great character,” Queiroz added.“When it’s necessary to play, they play. When it’s necessary to fight, they fight. Now they must be ready to play the game that is in front of them.”“We will try to be mentally fresh for the next game because now the real Asian Cup starts. From now on, only the team that wins will survive,” the Iran coach said.“For us, our goal was to qualify. After the first two games, we felt that we could be top of the group. Another goal was to give the opportunity to some players against Iraq. We made five changes. All of them showed that they are ready to compete.”
Newcastle manager Rafa Benitez says he was surprised Fabian Schar’s solo goal in their 3-0 home win against Cardiff City on Saturday.Benitez praised Schar for his moment of individual brilliance after he scored a stunning goal against Cardiff City at St James Park.Schar went on a 40-yard dribble before sending the ball flying into the bottom left corner, leaving Cardiff City goalkeeper Neil Etheridge helpless.The defender also scored in the second half to complete his brace and to double Newcastle’s advantage. Ayoze Perez completed the scoring in stoppage time to make it 3-0.“Not the first one,” Benitez told Sky Sports when asked if he knew Schar had the ability to score such a goal.“You can expect him to score maybe from a corner but he’s a player with quality and he was going forward. It was a great goal.”Premier League Betting: Match-day 5 Stuart Heath – September 14, 2019 Going into the Premier League’s match-day five with a gap already beginning to form at the top of the league. We will take a…Newcastle United climbed out of the relegation zone after their first win in nine Premier League games, and Benitez was delighted with the result.“We played extra-time in the FA Cup and scored four goals – that gave everyone confidence today,” he said.“We could see from the first minute our team wanted to get three points against a rival. We did really well. Everyone has to be pleased.“My message to the fans was to stay calm and support the team – the players did well and the fans enjoyed every minute.”
The Celtic goalkeeper broke his arm while battling for the ball with Jermain Defoe and he was out for three monthsExactly nine years ago, Craig Gordon was Sunderland’s goalkeeper and he got his arm broken after a collision with Tottenham Hotspur Jermain Defoe.“I got to the ball first and he got their second and broke my arm. That was a bad break and I had to get a metal plate inserted in my arm,” Gordon told The Chronicle Live.“I was out for another three months and came back and played the rest of the season with the metal plate.”“That summer I got the metal taken out of my arm and very soon into pre-season the arm broke again and that was another three months when it got put back in again,” he added.Johnston is disappointed after being injured Manuel R. Medina – September 11, 2019 Celtic winger Mikey Johnston was disappointed to miss Scotland Under 21 national team’s victories over San Marino and Croatia, and he hopes he can return to play soon.“That was the third operation on my arm and that was frustrating. The metal plate is still in there today so I have not had any more trouble with it.”“Every time I felt like I was getting to a point where I was putting in good, consistent performances, something else would come up,” he commented.“I was starting to play in games where I probably wasn’t fit and I was starting to think whether this would ever be fixed.”“This was a very long-term thing and perhaps it was something I wouldn’t come back from,” he added.“There had been so many things that had gone wrong I felt I had to leave.”
The former Manchester United manager believes that people learn more by winning that by losing in the world of football.Portuguese coach Jose Mourinho has always been very charismatic and controversial.And after he was sacked by Manchester United, he started working for TV channel DAZN.“People used to say that you learn more with defeat. Maybe there is some truth in it,” he told The Telegraph.“I feel my natural habitat is winning. This is the first time when I didn’t win any trophy for 18 months. Some guys don’t win any trophies for 18 years. I didn’t win any trophy for 18 months.”“Now I have time for thinking, reflection, trying to understand everything and trying to be more ready for the next one that is coming. I know it is coming. It hasn’t come yet because what has come along, I didn’t want,” he explained.Liverpool legend Nicol slams Harry Maguire’s Man United form Andrew Smyth – September 14, 2019 Steve Nicol believes Harry Maguire has made some “horrendous mistakes” recently, and has failed to find his best form since joining Manchester United.“I want to work in a club that understands there is a structure in place. I don’t want to work in a structure of no coincidence [unity] in the thinking.”“People sometimes say ‘this manager doesn’t like to work with a football director’; ‘this manager doesn’t like to work with chief scout’; ‘this manager doesn’t like to work with an owner’; ‘this manager doesn’t like to work with the president’,” he commented.“During my career, I have been working in every possible circumstance. The most successful situations are not because of the structure but because of the empathy in the structure.”“People who work well together. People who share the same kind of ideas. This is the fundamental thing,” he added.“You now have a generation of players who are not just players but the whole package. You have the player, the family, the agent, the entourage, the director of communication. You sometimes have the individual’s medical people and in an extreme situation you even have what they call their ‘personal fitness guys’.”“When you have a player you have all these distractions. And if there is no empathy in the structure of the club you get into so many contradictions that it is really, really difficult to work.”
Facebook The GRAMMY-winning songwriter/guitarist will be releasing a greatest hits album and touring North America this fall in supportAna YglesiasGRAMMYs Aug 14, 2018 – 5:39 pm The former Fleetwood Mac guitarist Lindsey Buckingham announced today that he will be releasing Solo Anthology: The Best of Lindsey Buckingham this fall, and touring North America in support of the album. https://twitter.com/LBuckingham/status/1029427791912165377 News Twitter The collection, which will be available Oct. 5 both digitally and as a three-disc set, will include two previously unreleased songs, plus remastered and live versions of Buckingham’s hits spanning his career, from his 1981 solo debut album Law And Order to his 2017 duet album with former-bandmate Christine McVie. A special vinyl version will also be available at a later date.Buckingham began making music with Fleetwood Mac when he and Stevie Nicks joined the band in 1975, helping write many of their hits, including GRAMMY-nominated classic “Go Your Own Way.” Fleetwood Mac, along with Buckingham, was honored as the 2018 MusiCares Person of the Year, the first ever band to receive the award.The tour will begin on Oct. 7 in Portland, Ore., with tickets on sale this week. All tickets purchased will include a copy of the new album; to purchase tickets and for more information, visit Buckingham’s website.Catching Up On Music News Powered By The Recording Academy Just Got Easier. Have A Google Home Device? “Talk To GRAMMYs”Read more Lindsey Buckingham Announces Solo Tour, Anthology lindsey-buckingham-announces-tour-and-solo-anthology Lindsey Buckingham Announces Tour And ‘Solo Anthology’ Email
Facebook System Of A Down Reunite For Sonic Temple 2019 sonic-temple-2019-lineup-system-down-lamb-god-more Email https://twitter.com/SonicTempleFest/status/1067059068550828032 Twitter Sonic Temple 2019 Lineup With System Of A Down, Lamb Of God, More News Ohio hosts 2019’s inaugural hard-rock festival experience — its stacked lineup reveals a debut with a pedigreePhilip MerrillGRAMMYs Nov 26, 2018 – 1:51 pm Danny Wimmer Presents has announced the lineup for the Sonic Temple Art & Music Festival to be held in Columbus, Ohio on May 17–19, 2019, including the reunited System Of A Down, plus other GRAMMY winners Foo Fighters, Ghost, Halestorm, and Tom Morello.While replacing the successful 12-year run of Rock On The Range, Sonic Temple aims to be more than just a festival with expanded art, comedy and food experiences.”Although in its inaugural year, Sonic Temple’s pedigree is proven, and its roots are strong,” said System Of A Down’s Shavo Odadjian. “It made total sense for us to be involved.”That pedigree has also drawn GRAMMY nominees Disturbed, Gojira, Joan Jett And The Blackhearts, Killswitch Engage, Lamb Of God, Mark Lanegan Band, Meshuggah, and The Prodigy. The exciting array of rockers also includes Action Bronson, Beartooth, The Black Dahlia Murder, Bring Me The Horizon, Chevelle, The Cult, Pussy Riot, Yungblud, and many more.The fest’s SiriusXM Comedy & Spoken Word Tent will host, among others, GRAMMY winner Henry Rollins, GRAMMY nominee Andrew Dice Clay and Pauly Shore.Tickets for the inaugural experience go on sale at the Sonic Temple Festival website on Nov. 30 at noon, eastern time.Black Dahlia Murder: For The Love Of Melodic MetalRead more
Reserve Bank of India (RBI) governor Raghuram Rajan opposed recommendations in the BN Srikrishna Committee report, and termed merging of all regulators into one entity as “schizophrenic”.The report was submitted in March 2013. Rajan debated regarding the recommendations mentioned in it during an industry event in Mumbai on Tuesday. Financial Sector Legislative Reforms Committee (FSLRC) report is important in the financial history but most of the recommendations are “faddish” and “impressionistic” than scientific, according to Rajan.The RBI governor points out two “fundamental areas of tension” from the report in his speech. One is the size and scope of regulators and the other is the negligence of regulators. Rajan claims the report does not give importance to the magnitude of synergies gained or lost.”It emphasizes synergies in bringing together some regulators into one entity. But in the process it suggests breaking up other regulators, with attendant loss of synergies,” he pointed out.The report suggests that laws which do not micromanage, gives regulators the freedom to fill in the details, in accordance with the changing needs of the economy.Speaking of this suggestion, Rajan stated: “At the same time, the FSLRC wants to check and balance the activities of regulators through judicial oversight. Too much of checks and balances could completely vitiate the flexibility afforded by rewriting laws.”Rajan opposed the recommendation mentioned in the report that merging of all regulation of trading will be done under one roof and consumer protection regulation under another. According to him, if it is implemented, then it will slow down the consistency and development of the market.The RBI governor said if the government wants to manage its own debt, then the RBI will not come in its way.”I don’t believe the government suffers any less from conflicts of interest in debt management (unlike the views of the FSLRC), but the RBI could well carry out the government’s instructions without any loss in welfare,” he said.Rajan was not in favor of implementing such recommendations as according to him, if something is not broken, there is no need to fix it.”As the Chinese would say, let us recognize the value of crossing the river by feeling each stone before we put our weight on it. Let us not take a blind jump hoping that a stone will be there to support us when we land. Or in American, if it ain’t broke, don’t fix it!” he said.
2NTR Kathanayakudu$482,599 8Jersey$144,687 3Dear Comrade$273,000 1Maharshi$516,441 2Mahanati$303,456 7Oh Baby$148,589 5NOTA$128,760 1Geetha Govindam$377,930 4F2 – Fun and Frustration$259,433 RankMovieCollection RankMovieCollection 3Dear Comrade$273,000 4Arjun Reddy$194,051 Dear ComradeTwitterVijay Devarakonda-Rashmika Mandanna’s Dear Comrade started with a bang and made a superb collection at the USA box office in the premiere shows. It has beaten the record of F3 – Fun and Frustration and become the third biggest opener of 2019 in the country.Geetha Govindam is a blockbuster at the USA box office and the sparkling chemistry between Vijay Devarakonda and Rashmika Mandanna is one of the biggest factors, which contributed to its huge success. The hit couple is back together with Dear Comrade and their presence created a lot of hype. Besides the film is simultaneously released in Telugu, Tamil, Malayalam and Kannada languages.Hence there was a huge demand for the overseas theatrical rights of Dear Comrade and several leading distribution houses were vying their hands for its rights. But Sarigama Cinemas clinched them for a whopping price of Rs 3.50 and planned to release it in over 220 screens across the USA, the UK, the UAE, Australia and other foreign markets in a bid to cash on huge hype surrounding the movie.The hype helped Dear Comrade to make a good advance booking for its opening weekend with its pre-sale business crossing 250,000 hours before its preview shows began. The distributors held a large number of premiere shows across the USA on Thursday, a day before its release in India. The movie witnessed massive response in all the cinema halls and some centres ran to packed houses.The distributors are yet to reveal their business details. If we are to go by early trends, Dear Comrade has collected $273,000 at the USA box office in the premiere shows. A film critic with Twitter handle @benny_speaks tweeted, “#DearComrade USA premiere Gross at 8 PM: $273,000 from 172 locations @TheDeverakonda @MythriOfficial @iamRashmika @bharatkamma.”When the final figures are revealed, Dear Comrade will easily cross $300,000 mark at the USA box office in the premiere shows. The movie has beaten the records of Arjun Reddy, Nota and Taxiwaala and become the third biggest opener for Vijay Devarakonda after Mahanati and Geetha Govindam.Here are Vijay Devarakonda’s top five biggest openers at the USA box office.RankRankMovieMovieCollectionCollectionRank1MovieGeetha GovindamCollection$377,930Rank2MovieMahanatiCollection$303,456Rank3MovieDear ComradeCollection$273,000Rank4MovieArjun ReddyCollection$194,051Rank5MovieNOTACollection$128,760Rank6MovieTaxiwaalaCollection$94,270 5Vinaya Vidheya Rama$181,118 6Majili$162,542 6Taxiwaala$94,270 9NTR Mahanayakudu$102,234 If we are to go by the early trends, Dear Comrade has already beaten the opening records of Varun Tej’s F2 – Fun and Frustration and Ram Charan’s Vinaya Vidheya Rama at the USA box office. It has become the third biggest opener of the year. Here is the list of top 10 biggest opener Telugu Movies in USA – 2019.RankRankMovieMovieCollectionCollectionRank1MovieMaharshiCollection$516,441Rank2MovieNTR KathanayakuduCollection$482,599Rank3MovieDear ComradeCollection$273,000Rank4MovieF2 – Fun and FrustrationCollection$259,433Rank5MovieVinaya Vidheya RamaCollection$181,118Rank6MovieMajiliCollection$162,542Rank7MovieOh BabyCollection$148,589Rank8MovieJerseyCollection$144,687Rank9MovieNTR MahanayakuduCollection$102,234Rank10MovieLakshmi’s NTRCollection$90,770 10Lakshmi’s NTR$90,770
Citation: Managing complexity: Novel protein folding tool vastly simplifies understanding how sequence encodes structure (2016, November 29) retrieved 18 August 2019 from https://phys.org/news/2016-11-complexity-protein-tool-vastly-sequence.html (Phys.org)—Protein folding is the process by which a polypeptide (a linear organic polymer chain consisting of many amino acid residues, or monomers) transforms from a random coil into the 3D conformation in which it can perform its biological function. Since different proteins fold into a range of very different shapes, the Protein Data Bank (PDB) – a database archive comprising experimentally-determined three-dimensional structures of large biological molecules, including numerous protein conformations – can be disarmingly complex. This is problematic because that space is fundamental to understanding how sequence encodes structure. Recently, however, scientists at Dartmouth College deconstructed the universe of known protein structures into reusable building blocks that they term tertiary structural motifs, or TERMs. (Structural motifs are compact blocks of a 3D protein structure.) They found that 50% of PDB protein conformations were described – at sub-Angstrom resolution – by a surprisingly small group of roughly 600 TERMs. Moreover, TERMs allowed them to discern sequence–structure relationships. The researchers state that these results can be used for protein structure prediction, protein design and other applications. In addition, some 600 TERMs describe 50% of the known protein structural universe at sub-Angstrom resolution. “This refers to the level of degeneracy we discovered in the protein structure space.” That only ~600 TERMs are required to describe half of all residues and inter-residue contacts in known protein structures suggests that at the local structural level, there just are not that many structural patterns that naturally emerge. There are, of course, a large number of more rare geometries, and full coverage of the protein structural universe requires tens or even hundreds of thousands of TERMs – but nevertheless, the majority of protein structure does appear to be quite degenerate at the local level.”As to the specific implications of their study for protein structure prediction, protein design, and other applications, Grigoryan points out that the major implication for protein design and structure prediction is the novel means of mining for sequence-structure relationships. “Statistical potentials, derived from known protein structures, have been employed for decades in both of these applications. However, such potentials typically describe the statistics associated with isolated simplistic structural features, like dihedral angles, individual interatomic or interresidue distances, or burial environments. However, TERMs offer the potential to describe sequence statistics in the context of holistic structural environments, which would be much more useful for both design and prediction.” Specifically, he explains, in design, this would allow for a better understanding of what sequences would or would not form the target structure; for prediction, it would help drive structural sampling towards structures whose TERMs are most consistent with the modeled structure. “A potential limitation is the amount of available data, because not all TERMs have sufficient known instances to synthesize accurate sequence models,” he acknowledges. “However, the early results shown in our paper, as well as some unpublished results in our lab, point to the fact that TERM-based statistics are already providing non-trivial insights that in many cases, other methods are unable to easily capture – and this is only going to get better as the amount of structural data continues to accumulate.”When asked about the implications of their work for synthetic genomics and synthetic proteomics, Grigoryan said “It’s a good question. I can certainly see a future in which a truly robust method for computational protein design serves as a key element in synthetic genomics and proteomics applications. I’d say that in terms of our current design techniques, we’re not quite there today – but our goal with TERM-based and other developments – as well as the general goal of our field – is certainly to keep improving the robustness of our methods, so that one day, we can offer them as black-box solutions to folks in other disciplines, whether that be materials science, biomedicine, or synthetic biology.”Moving forward, Grigoryan says that the team is focused on extending the capabilities of their TERM-based techniques to both protein design and structure prediction. “We’re also very interested in introducing ensemble-based modeling approaches into protein design: Since protein structural states are really conformational ensembles, the language of statistical mechanics is most appropriate for describing their behavior. Therefore, we’re pursuing methods for introducing statistical mechanics-based calculations towards improving the accuracy and robustness of protein design methods.”In addition to protein design and structure prediction, Grigoryan sees their study as having strong implications for our fundamental understanding of protein structure in general. “I think the new look at the protein structural universe our study offers can help not only with modeling and designing proteins, but it can also help with teaching about protein structure. The ideas of modularity and representation of standard motifs,” he concludes, “have already made their way into my own teaching here at Dartmouth.” Fig. 1. Discovering TERMs that optimally describe the protein structural universe. (A) A candidate motif is defined around each residue in the database, structural matches (from within the database) to each motif are identified using MASTER (58), and these matches are used in defining the coverage of every motif. Next, the set cover problem is solved to find the minimal set of motifs that jointly cover the structural universe. (B) Coverage of the universe as a function of the number of TERMs, in the order discovered by the greedy algorithm (inset uses logarithmic scale along the x axis). Mackenzie CO, Zhou J, Grigoryan G (2016} Tertiary alphabet for the observable protein structural universe. Proc Natl Acad Sci USA 113(47):E7438-E7447. Fig. 2. Universal TERMs. (A) Top 24 TERMs ranked by the number of elements covered in the set cover procedure; jointly these cover roughly a third of the universe elements. (B) A diverse selection of high-priority TERMs that span from one- to five-segment motifs, shown in the first to fifth columns, respectively. Shown in each column are representatives from the three most common secondary-structure classes for the given number of segments (SI Appendix, SI Methods). In both A and B, each TERM is represented with ten randomly chosen matches along with its centroid. The text underneath each TERM is formatted as follows: r; n (s/c) where r is the rank of the TERM in the set cover (lower rank corresponds to higher priority), n is the number of unique matches, s is the total fraction of universe elements covered by the TERM, and c is the marginal fraction of the universe elements covered by the TERM (i.e., fractional coverage of those elements not already covered by preceding TERMs in the set cover). Mackenzie CO, Zhou J, Grigoryan G (2016} Tertiary alphabet for the observable protein structural universe. Proc Natl Acad Sci USA 113(47):E7438-E7447. Grigoryan adds that by using residues and contacts rather than an a priori structural alphabet, defining the motif candidates was much easier. “It seemed particularly natural to define one candidate motif for every residue in the structural database,” he notes, “such that the motif would capture the residue and all of its contacts – that is, the motif would describe that residue’s local structural environment.” More information: Tertiary alphabet for the observable protein structural universe, PNAS November 3, 2016, Published online before print, doi:10.1073/pnas.1607178113 Researchers find possible universal code of protein structure A key finding discussed in the paper was that universal TERMs provide an effective mapping between sequence and structure. “Because universal TERMs recur many times in unrelated proteins,” Grigoryan tells Phys.org, “compiling the list of occurrences of each TERM allows us to start gleaning sequence rules that may underlie each of these structural motifs. The question was whether these sequence rules reflected fundamental determinants of structure, or simply noise from a limited structural database potentially biased by arbitrary evolutionary choices or the selection of proteins whose structures have been solved.” The team resolved this through a series of experiments in which they demonstrated that a significant component of the sequence statistics emerging from TERM matches does likely emerge from fundamental sequence-structure relationships.In effect, the natural utilization of TERMs provides a means of uncovering sequence–structure relationships. “Let’s say a given TERM is consistent of a two-strand beta sheet interacting with an alpha helix at a particular characteristic crossing angle and distance,” Grigoryan illustrates. “If we happen to have, for example, 600 instances of this motif from unrelated proteins, we essentially have 600 different examples of nature having made this structure with different amino-acid sequences. We can then use these 600 sequences to begin to understand what sequence features may be required or preferred to form such a structure – and we can do this for any TERM with sufficiently high usage in nature.”It turns out that by using this approach systematically for all TERMs contained in a given protein backbone structure, sequence variability predicted from TERM data agrees closely with evolutionary variation. “We can deduce a statistical model of what sorts of sequences would be likely to fold to that structure,” he explains. “If we then ask this model to produce a whole bunch of such sequences, we find that the emergent sequence variability is often in close agreement to the evolutionary variability observe for the corresponding protein.” © 2016 Phys.org This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Prof. Gevorg Grigoryan discussed the paper that he and his co-authors published in Proceedings of the National Academy of Science of the United States of America. One of the primary challenges in their study was decomposing the set of known protein structures into standard reusable tertiary structural motifs. “The main challenge here was probably knowing where to begin,” Grigoryan tells Phys.org. “Our overarching goal was to describe, in his words, an alphabet of protein structure.” However, he points out that – unlike with text – the researchers were not able to visually determine where one structural unit (metaphorically a letter) began and another ended. “The number of ways in which we can potentially partition protein structure is extremely large, and so the task of finding a good decomposition seemed overwhelming.”The scientists addressed this problem by not defining a priori what the letters of the structural alphabet should be, but rather defining the task that these letters should accomplish – that is, describing the set of all residues and residue pair contacts observed in known protein structures. Next, they selected the smallest set of reusable building blocks they’re named tertiary structural motifs, or TERMs, that would achieve this goal.Another hurdle in determining the set of universal TERMs that capture all structure in the PDB was the difficult task of sifting through 13 million candidate TERMs, and describing which residues and contacts in known protein structures they individually explained. “Our previously-developed, efficient structure search algorithm MASTER helped us resolve this – but the total amount of computational time involved was still quite large, so we had to make use of a computer cluster.” A computer cluster is a single logical unit comprising multiple networked-linked computers. Explore further Fig. 5. An EF-hand TERM. (A) The 31 nonredundant EF hand-containing instances of the TERM (gray) with adjacent structure (green). Calcium atoms from TERM instances are shown as yellow spheres. (B) TERM instances alone with calcium-contacting side chains shown with sticks. (C) Variability among TERM instances. Four instances are shown in gray: two EF-hand examples with varying loop geometries (surrounding structure in green) and two non–EF-hand instances (from PDB ID codes 3HNO and 1CB7, surrounding structure in cyan), including one with TERM segments belonging to different chains. (D) Sequence logo of nonredundant EF hand-containing matches of the TERM. Position 18 corresponds to the canonical EF hand loop position 1 (61). Mackenzie CO, Zhou J, Grigoryan G (2016} Tertiary alphabet for the observable protein structural universe. Proc Natl Acad Sci USA 113(47):E7438-E7447. Journal information: Proceedings of the National Academy of Sciences
“We have decided to come up with a notification to ban chewable tobacco in all forms from Monday in Delhi. Under this, no one will be allowed to sell, purchase or store chewable tobacco,” Delhi Health Minister Satyendra Jain told reporters on Friday.He said enforcement teams of Delhi Police as well as the health department have been asked to conduct surprise inspections across the city to ensure that the ban is implemented. “The teams have been told to be active on this,” Jain said. However, no such ban will be enforced on cigarettes. Health Department officials said there was a Delhi government notification in September 2012 which was in pursuance of a series of directions from the Supreme Court to ban gutkha in the city. Also Read – Need to understand why law graduate’s natural choice is not legal profession: CJIBut since the ban mentioned the term “gutkha”, the tobacco retailers started selling the components of gutkha (betel nut and raw tobacco) in separate pouches. So, the purpose of banning gutkha was not served. Therefore, the health department last year started with a new proposal to ban all raw chewable tobacco products in Delhi, a senior official said.According to officials, gutkha is also being supplied to retailers in Delhi from neighbouring states of Uttar Pradesh and Haryana. Stepping up its efforts towards tobacco control, the health department has also launched an innovative drive, creating a ‘Tobacco Aware Citizens’ Directory’ to spread an awareness about its harmful effects.Sources in the government said the ban on the sale, purchase and storage of chewable tobacco in all forms would be for the next one year and thereafter, the government will re-notify it. “Lieutenant-Governor Najeeb Jung has already given his nod and the government will issue the notification to ban chewable tobacco in all forms from Monday,” said a senior government official.
Kolkata: The South 24-Parganas district administration is leaving no stones unturned to ensure a good turnout in the last phase of the Lok Sabha polls scheduled on May 19.The district, with the four parliamentary constituencies of Diamond Harbour, Jadavpur, Mathurapur, Joynagar and almost half of South Kolkata, has the highest number of booths in the entire country at 8,550. The district is followed by Nagpur, North 24-Parganas and Thane in terms of total booth count, nationwide. Also Read – Rs 13,000 crore investment to provide 2 lakh jobs: Mamata”Apart from mobilising more than 6,000 vehicles including water transport and other arrangements for smooth ferrying of polling personnel, we have given utmost importance to risk aversion and disaster prevention. We are installing two temporary automatic weather stations at Gosaba and Patharpratima, for very specific and localised weather forecasts,” said South 24-Parganas DM Y Ratnakara Rao, who is also the District Election Officer (DEO). The district administration has taken lessons from cyclone Fani, for which it had elaborate arrangements for disaster management. “This district has perhaps the highest diversity in the country, with a blend of metropolitan, international maritime border sharing, as well as an archipelago of islands,” the DM added. Also Read – Lightning kills 8, injures 16 in stateThe entire Gosaba Assembly constituency under Joynagar PC which has 257 booths and nearly half of the Patharpratima Assembly constituency with 136 out of 293 booths, are located in remote riverine locations. “Arrangements are in place to make voting personnel reach these locations 48 hours in advance. The rule book says that voting personnel should reach their place of duty a day before polling,” a senior official in the district administration said. The official added that there will be speedboats at all important ghats, ‘Apatmitras’ who are specially trained in disaster management operation and other necessary standard operating procedure (SOP) in place. Sufficient number of CCTVs will also be installed at important locations. The Coast Guard, which has its base at Frasergunj, is sanitising the waterways on a regular basis as a part of preventive intervention. “We have made all DCRCs weather proof, taking lessons from the 2009 Lok Sabha elections when 200 EVMs were damaged due to inclement weather and machines were procured from Hyderabad on a war footing to address the crisis situation. With a large part of the district being located on the coastal belt, chances of natural calamity are always on the cards. So we need to be prepared fully in advance,” the official said.
Travelweek Group Tags: Canada Jetlines, Jetlines VANCOUVER — Canada Jetlines says it intends to provide future service to several sun destinations in Mexico including Puerto Vallarta, Los Cabos and Cancun.The start-up ultra low-cost carrier, currently aiming for a summer 2019 launch, says it has reached agreements with Grupo Aeroportuario del Pacífico to provide future service to the Puerto Vallarta International Airport (PVR) and the Los Cabos International Airport (SJD), as well as Grupo Aeroportuario del Sureste (ASUR) to provide future service to the Cancun International Airport (CUN). “We are thrilled to announce future service to these airports,” says CEO Javier Suarez. “I have worked in this market extensively and have a deep understanding of how to operate successful routes in and out of Mexico. We look forward to providing Canadians with ultra-low fares for their vacation plans. With the money saved, Canadians will have the ability to spend more at their destinations; staying longer or in nicer resorts with their friends and family members. Our low fares will also encourage Mexicans to visit beautiful Canada.”Suarez joined Canada Jetlines in June 2018, first as Chief Commercial Officer and later as CEO, from Mexican low-cost carrier VivaAerobus where he was Vice President, Network Planning, Revenue Management, E-Commerce.Grupo Aeroportuario del Pacífico CEO Raul Revuelta says, “We at GAP are pleased to welcome Jetlines at our Puerto Vallarta and Los Cabos airports. During 2018, for the first time in history, we received a combined traffic of 10 million passengers at both airports; this due to the growing number of hotel rooms and the high quality of the touristic products offered at these amazing destinations. I am sure that our Canadian friends will have a wonderful time while visiting Puerto Vallarta and Los Cabos, and we at GAP will continue to work to provide them with the best airport experience.”And ASUR’s Customer and Route Development Director Alejandro Vales said, “ASUR is delighted to welcome Jetlines to our Cancun airport. A brand-new Canadian airline bridging new origins from Canada to our world-class destination will be a recipe for success indeed.”The long list of carriers flying Canadian vacationers to Mexico got even longer this month with low-cost carrier’s Swoop’s new service to Cancun, Mazatlzan and Puerto Vallarta.Suarez says Canada Jetlines’ ability to service these routes is subject to the completion of the airline licensing process and the receipt of applicable regulatory approvals. It’s a crowded field but Canada Jetlines says it wants PVR, CUN & SJD Thursday, January 17, 2019 Share Posted by << Previous PostNext Post >>