The Madhya Pradesh government on Sunday cleared a proposal to enact a law for awarding death sentence to those guilty of raping girls aged 12 or below in the State. The moves comes in the wake of a spurt in rape incidents recently. “The Cabinet chaired by Chief Minister Shivraj Singh Chouhan okayed the recommendation to hand down capital punishment for rape of girls aged 12 years or below,” M.P. Finance Minister Jayant Malaiya told PTI. “We are going to present a Bill to this effect in the winter session of the Assembly beginning Monday,” he said. He said the Cabinet also decided to give harsher punishment to those guilty of molesting, stalking and harassing women. Now, a fine of ₹1 lakh will also be imposed on such offenders, he added. Once cleared by the Assembly, the Bill for capital punishment for rape of girls aged 12 or below will be sent to the Centre which will send it to the President for his approval.Facing criticismThe Madhya Pradesh government had recently come in for criticism over incidents of rape. A 19-year-old UPSC aspirant was allegedly raped when she was returning home from a coaching institute on October 31 here. After public outrage, some police officers were suspended and transferred for the delay in registering an FIR. The National Crime Records Bureau (NCRB) data for 2015 showed that Madhya Pradesh reported the highest number of rape cases (4,391) in the country.According to the NCRB data for 2014, the State reported 5,076 rape cases, which was 14% of the total rape incidents reported in the country.
anurag 0 SHARE SHARE EMAIL Published on sport Supreme court had slapped Thakur with contempt and perjury notices for filing a false affidavit over writing to the ICC on the issue of autonomy. Apex court accepts Anurag Thakur’s apology, drops contempt proceedings against him anurag Former BCCI President Anurag Thakur, who is facing contempt notice for filing a false affidavit in the Supreme Court, today tendered “unconditional and unqualified apology” before it.Thakur, who was present in the court, said he had never intended to file any false information before the apex court and filed an affidavit explaining the circumstances under which the averments made by him led to the initiation of contempt proceedings.“I (Thakur) have tendered my unconditional and unqualified apology and I have explained the circumstances. I had not intended to file any false information,” senior advocate P S Patwalia, appearing for Thakur, told the bench headed by Justice Dipak Misra.The bench, also comprising Justices A M Khanwilkar and D Y Chandrachud, fixed the matter for hearing on April 17 and also exempted Thakur from personal appearance on that day.The apex court had on January 2 come down heavily on the defiant BCCI brass and removed Thakur and Ajay Shirke as the President and Secretary for “obstructing” and “impeding” its directions for overhauling governance in the cricket body.The bench had slapped Thakur with contempt and perjury notices for filing a false affidavit over writing to the ICC on the issue of autonomy. × SHARE COMMENTS March 06, 2017 Supreme Court sacks Anurag Thakur, Ajay Shirke from BCCI Battle with court not personal, says ousted BCCI chief Anurag Thakur RELATED null COMMENT
Get the best of News18 delivered to your inbox – subscribe to News18 Daybreak. Follow News18.com on Twitter, Instagram, Facebook, Telegram, TikTok and on YouTube, and stay in the know with what’s happening in the world around you – in real time. Bengaluru: Boasting of five India internationals in their ranks, including talismanic captain Sunil Chhetri, a formidable Bengaluru FC will begin their quest for title defence when they take on NorthEast United in their opening Indian Super League match here on Monday.The Bengaluru-based side have been synonymous with consistency in India domestic football history. After three years of success in the I-League, they joined ISL in 2017 and made an instant impact. Guided by Spanish coach Albert Roca, they put up a splendid show in their first season and topped the league phase standings though they suffered a heartbreaking loss in the final to Chennaiyin FC at home.The next season (2018), Bengaluru had Roca’s protege Carles Cuadrat under whom they defeated FC Goa to clinch their maiden ISL title.With a clutch of new signings and retention of key players, particularly domestic, Bengaluru look set to dominate again this season. They roped in India midfielder Ashique Kuruniyan this season.With an all-Indian attacking line-up of Chhetri, Udanta Singh and now Kuruniyan, the defending champions look formidable on paper.There were five Bengaluru FC players in Igor Stimac’s starting XI that played the first two World Cup qualifiers with captain Chhetri, Gurpreet Singh Sandhu, Udanta, Rahul Bheke and Kuruniyan playing a significant role.The Blues have added striker Manuel Onwu of Spain, who will have the unenviable task of replacing the prolific Miku, who has left the side.Beangaluru FC registered a come-from-behind win against NorthEast United in the two-legged playoff en route the final last season. But it will not be easy for the home side to beat NorthEast United on Monday.Despite the departure of some key players of the previous season, NorthEast United have made some big signing, including high profile Ghanaian Asamoah Gyan.Bengaluru head coach Cuadrat said it’s “strange” that none of the teams have been able to retain their title in the ISL.”I tell my players to be competitive so that we can reach the play-offs. No team has won it twice. It is a strange thing. It’s not our job to defend the title but right now (the job is) to reach the play-offs. After that we will do our best to win the title,” said the Spaniard.”NorthEast United is a completely different team with a different coach. It is going to be a tough game for us. We have no idea about what NorthEast is going to offer. They have made some good signings like Asamoah Gyan.”On the other hand, NorthEast United’s new head coach Robert Jarni is confident of a winning start at the Sree Kanteerava stadium.”This will be a different game. We believe that we can do something good against them. We are confident and we will try to bring the three points.”The former Croatian international and Real Madrid wing back, who took over from Eelco Schattorie, felt his side will have a slight advantage since most of Bengaluru’s key Indian players were away with the national team for a while and might not have had tuned into their side’s preparations.”Yes, it will be a little advantage for us. As a coach, you want to have the full squad for training. But they could not have that because of the international break. But they have good players who know the coach and they are playing together from last season. It might help a little, but it is definitely not going to make a big difference,” Jarni said.”My team is still young and I am still trying to influence my philosophy on them. This is my first season with this team. There are new players, so it is going to be difficult and we need time. Related StoriesISL Introduces ‘Cooling Breaks’ in Accordance with FIFA RulesNita Ambani Wishes to Take Indian Super League to Middle East bengaluru fcfootballIndiaindian football First Published: October 20, 2019, 11:28 PM IST
NEW DELHI: The Delhi government is all set to launch more than 100 Mohalla Clinics by next month, said the sources in the government. All these clinics are mostly ready for the use and now the government is working on the appointment of doctors in these clinics and also some last-minute infrastructural work is going on. “Most of these Mohalla Clinics are fully ready. The Public Works Department (PWD) is working on the last minute setting of furniture in these clinics. The work of appointment of doctors are also going on,” said a senior official. Also Read – After eight years, businessman arrested for kidnap & murderAccording to the officials, most of these clinics are built in both government lands and rented lands. “The government has now decided to rent private lands because the projects got delayed due to the availability of the lands. Now after the decision of taking lands in rent, the work progress is going fast,” said the official. The Delhi government will also extend the timings of Mohalla or neighbourhood clinics, and in effect starting a second shift in them to cater to excessive demand. The existing clinics, each seeing visits by at least 150 patients a day will be open from 7 am to 7 pm, six days a week. Mohalla Clinics of Delhi, the flagship project of Delhi Chief Minister Arvind Kejriwal will also get an up gradation where the various important tests for the patients would be outsourced to the private labs. Tenders have also been issued for outsourcing laboratory services for the clinics and mobile health services. This will make the tests faster and perfect. Also Read – Two brothers held for snatchings”The Delhi government tries to give all the tests facilities at the Mohallah Clinics but in some places, we face problems due to lack of technicians. Now if we can outsource these tests it will help the patients and also bring down the rush,” said an official. Meanwhile, after lots of tussle with the DDA the Delhi government has decided to take semi-commercial spaces on rent to make MohallahClinics. By November, the Delhi government will make 500 more Mohallah Clinics, said the sources in the Delhi government. In an urgent meeting with the Health Minister, the department took the decision.
Rabat – The government is “intensifying efforts to become one of the 50 best economies in the world in terms of the quality of the business climate by 2021, by engaging in structural reforms of Moroccan business,” Morocco’s Head of Government Saad Eddine El Othmani said Monday.El Othmani’s statements came in response to a question on “business climate reforms” during the monthly general policy session at the House of Representatives.Morocco jumped 9 places and ranked 60th out of 190 countries in the World Bank’s “Doing Business.” Improving its 2018 global ranking of 69th by nine places and two points, Morocco owes its score of 71.02 out of 100 to several new entrepreneurship-friendly policies. The North African country scored 67.91 points last year.Thanks to these reforms, Morocco ranked the second best country for doing business in the MENA region behind the United Arab Emirates and came third in Africa behind Mauritius and Rwanda.Read also: Morocco Jumps 9 Places, Ranks 60th in World Bank ‘Doing Business’ ReportEl Othmani explained that the state will promote international best practices in the business world, such as “simplification and digitization of administrative procedures, the modernization of the company’s legal and legislative frameworks, the universalization of the single portal as well as the improvement of benefits in their favor.”El Othmani also listed some important steps such as “reducing the cost of setting up a business through the exemption of registration fees; the facilitation of the transfer of ownership; the improvement of transparency in the land register and titling; simplification of export and import operations, and improvement of the infrastructure of Tangier-Med port.”To achieve Morocco’s strategic objective, the head of government affirmed that the national committee for business environment will implement the reforms programmed in the second part of the 2018-2021 action plan.In addition, El Othmani emphasized that an action plan will study all the indicators in the Doing Business report.Read also: Business Credit a “Reasonable Risk” in Morocco: Coface Risk AssessmentAccording to the 2019 Doing Business report, released Wednesday, October 31, Morocco has made it easier to start a business by reducing registration fees, streamlining procedures to register property, and improving the system to resolve insolvency.“The achievements have allowed Morocco to occupy very advanced positions on a global scale concerning indicators related to granting building permits (18th), tax payment (25th), business creation (34th), connection to the electricity grid (59th), foreign trade (62nd), investor protection (64th), and ownership transfer (68th),” the head of government said.
US Ambassador Atul Keshap met the Minister of Megapolis and Western Development Champika Ranawaka today and discussed several matters including progress on the development of a new constitution.The US Embassy in Colombo said that Ambassador Keshap and Minister Ranawaka also discussed future infrastructure projects essential to Sri Lanka’s prosperity, energy production and environmental protection. Ambassador Keshap stressed “the United States supports the Sri Lankan voters’ vision of a unified, peaceful, prosperous, and reconciled Sri Lanka with equal opportunity and human rights for all, regardless of ethnicity or religion.” (Colombo Gazette)
Jan Pronk, head of the UN Mission in Sudan (UNMIS), heard Mr. Kiir pledge to uphold Mr. Garang’s commitment to a peaceful and unified Sudan. Mr. Kiir had been named leader of the Sudan People’s Liberation Movement (SPLM) after Mr. Garang’s 30 July death.Mr. Kiir urged broad cooperation towards nation-building in Sudan and pledged to exercise his energies, and those of the SPLM, to bring eastern Sudan and the troubled Darfur region in the west on board the peace process. Darfur’s two-year conflict has claimed over 180,000 lives, displaced around 2 million people and sent hundreds of thousands more fleeing to neighbouring Chad.Mr. Garang, who steered the southern-based SPLM through a two-decade battle against the northern Government, had been instrumental in ushering in a January peace accord, which ended Africa’s longest-running conflict and led to the swearing in of a national unity Government in early July.His death, which occurred just three weeks after he took office as First Vice-President, sparked days of rioting in Khartoum and the southern part of the country and drew calls for calm and recommitment to the peace process from the UN Security Council, as well as Secretary-General Kofi Annan. The UN has pledged to assist the SPLM and the Government investigate what caused the helicopter to crash into a mountain in southern Sudan.
“Beyond the waters of the Nile, oil and minerals, Southern Sudan has a precious – an infinite – natural resource: the minds, the determination and the potential of her people, especially her children,” UN Children’s Fund (UNICEF) Deputy Executive Director Rima Salah said at Saturday’s launch of the ‘Go To School’ Campaign in Juba, the capital of Southern Sudan. Education is the key to future peace and prosperity in the region, where a 2005 accord between the Government and rebels ended a war that uprooted some 4.5 million people from their homes beyond its terrible death toll.The campaign aims to more than double the number of children in primary school during the course of the school year, which starts today. There are four times more boys than girls in school and only about 1 per cent of girls complete primary education.About 8,600 teachers, the majority untrained volunteers, cover approximately 2,000 schools. Many of these “schools” consist of little more than a blackboard propped under a tree. The campaign aims to deliver over 3.8 million textbooks and teachers’ guides and basic school supplies for up to 1.6 million children. From 6 million exercise books to 1.6 million pencil sharpeners, no child should go without the basics.Survey teams are roaming the vast region recording even the smallest schools under stress to produce a comprehensive list for planning purposes and to know exactly how many children are attending.Over 1,500 new classrooms are being constructed and accelerated training is underway for teachers and classroom facilitators. Public awareness campaigns are mobilizing children and parents to send their children to school, especially girls.The effort is led by the Government of Southern Sudan with the support of UN agencies, donors, non-governmental organizations (NGOs) and communities. Some $22 million has been received so far, with a similar amount still required to complete the targets for 2006.
MONTREAL – SNC-Lavalin is working hard to become an ethical benchmark for its industry by correcting the problems that have damaged the engineering company’s reputation over the past 18 months, its chief compliance officer said Monday.“We are well on our way and my perception is that our people, our employees, our executives completely understand what is required,” Andreas Pohlmann said after addressing a fraud conference in Montreal.The former head of compliance at Siemens said the process is never ending, but that SNC-Lavalin is progressing well in addressing its “compliance crisis” that tagged the company with accusation of bribery and corruption.Pohlmann has implemented a number of changes to reshape SNC’s ethical culture since joining the firm last March. These included a code of ethics and business conduct, an anti-corruption manual, a whistleblower hotline, ending payments to middlemen and implementing a 90-day amnesty program.Initial efforts launched in 2012 have accelerated this year and should allow SNC-Lavalin (TSX:SNC) to become a benchmark company for the engineering and construction industry in terms of ethics and compliance by early 2014, he said.SNC’s strategy is to develop one global compliance policy that is communicated to employees around the world. Personal training has also been provided in more than 40 countries in high-risk regions to arm employees with the tools to do business cleanly.Pohlmann said it’s naive to think that the ethical pressures are the same in North America as they are in difficult regions in Latin and South America, North Africa and Eastern Europe.“It’s our objective at SNC-Lavalin to help our employees to develop their own compass in terms of ethics and compliance,” he told the Association of Certified Fraud Examiners.He said the challenge is ensure that employees can respond positively to four questions: is what they are doing right for the company, is it consistent with the company’s core values, is it both legal and ethical and, most importantly, are they willing to be held accountable for their actions.Pohlmann said the “tone from the top,” including the board, CEO and senior executives is key to convincing employees to buy into the culture change because the company can’t afford more ethical breeches. He said chief executive Robert Card has insisted that the engineering firm is only interested in obtaining clean business.But he wouldn’t say if SNC-Lavalin’s past problems stemmed from the actions of a few individuals or the example set by the former board and executive team.“I don’t want to go into the details of the root causes of all of this. Let’s look to the future,” he told reporters, adding that being ethical is also good business.Pohlmann said he was “encouraged” by the level of participation in the company’s offer of amnesty by the Aug. 30 deadline, but declined to provide details.A World Bank official has begun on-site monitoring of SNC-Lavalin’s progress in implementing change as part of its settlement in April with the bank that included debarment for up to 10 years for its SNC-Lavalin Inc. subsidiary and several affiliates.Citing investment guru Warren Buffett, Pohlmann said a company’s reputation can take years to build up but little time to destroy.“In case of SNC-Lavalin it took over a 100 years to build a reputation but just…a few years, a few weeks, a few months to destroy it,” he said, noting how the Internet and social media send information about misconduct sweeping across the world.In addition to harming the company’s reputation, ethical problems can hurt its share price and market capitalization, cost millions in legal and consultant fees, reduce contracts and make it harder to retain and attract key employees.SNC-Lavalin created Pohlmann’s position nearly a year after an internal investigation uncovered $56 million in questionable payments.The discovery led to the departure of former CEO Pierre Duhaime who, along with former vice-president Riadh Ben Aissa, was charged with fraud over allegations that $22.5 million in questionable payments were used to win the Montreal super-hospital contract.SNC-Lavalin has sued Ben Aissa and former consultant Cynthia Vanier in an effort to recover more than $2 million, including $202,000 that it says was used to decorate a Toronto condominium owned by the son of Libyan dictator Moammar Gadhafi. The company alleges that the pair “conspired” with the company’s former vice-president, Stephane Roy, to use company funds without permission in a plot to smuggle Saadi Gadhafi to Mexico. by Ross Marowits, The Canadian Press Posted Sep 9, 2013 4:26 pm MDT AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email SNC-Lavalin working to restore reputation, executive tells fraud conference
Ohio State freshman defensive end Chase Young (2) sacks Maryland quarterback Caleb Rowe and forces a fumble during the Ohio State-Maryland game on Oct. 7. Ohio State won 62-14. Credit: Jack Westerheide | Photo EditorThere was a case to be made that Ohio State’s defensive end depth in 2017 was as strong as any in college football. It could even have been the best of the past several seasons.It not only had the 2016 Big Ten Defensive Lineman of the Year in Tyquan Lewis, but also the 2017 winner in Nick Bosa, as well as future NFL draft selections Jalyn Holmes and Sam Hubbard. Waiting behind the four starters were a pair of former top defensive end prospects in five-star freshman Chase Young and four-star redshirt freshman Jonathon Cooper, both of whom spelled the starters when needed.That depth was envious in 2017. It will not be there in 2018.Ohio State lost Hubbard to the draft while Holmes and Lewis both graduated, leaving Bosa, Young and Cooper as the only returning players at defensive end.“We’ll find some guys to play with them,” defensive line coach Larry Johnson said after the Cotton Bowl. “We’ll make some changes. We’ll make sure those guys have a chance to be fresh. We’re a long ways away from that, but I think we’ll be OK.”The concern with Ohio State’s defensive end group will not come from the talent present. Bosa and Young could be a dynamic pairing at the top, potentially the most explosive duo in college football, if the talent they have shown in the past continues in 2018. Cooper will present the Buckeyes with a strong third option in the rotation.And even though Young and Cooper have only part of one season full of garbage time minutes under their belts, they both feel ready to step into larger roles in the 2018 season.“I think we were prepared right now,” Young said after the Cotton Bowl. “But even this spring and this winter and the summer, it’s going to get us, and after all three of those [seasons], man, I think we going to be there. Just watch out.”The depth from there takes a bit of a hit and will remain questionable heading into the season.Since the bowl game in December, Ohio State has a clearer vision of who will be able to provide backup to next year’s starters. The Buckeyes brought in defensive end recruits four-star Tyreke Smith, four-star Tyler Friday and three-star Alex Williams. However, Friday will be making the change from defensive tackle to end while Williams might get a shot at playing tight end in college.Even with the recruits coming in, it seems unlikely any of them will have extended roles. None are as highly regarded as Young coming out of high school. Young appeared in 10 games and had 3.5 sacks while Cooper played in nine games.Still, that playing time proved valuable for the pair. It was given chances to play against collegiate competition — though almost always toward the end of blowouts. Bosa remembers that even when the game was not on the line, the playing time was important for his own development.“My freshman year, I was able to play a decent amount,” Bosa said. “Just get that big game experience. Just get used to the speed of the game. It’s a lot different than high school and you just learn a lot when you actually get in there, you can’t really replicate it in practice.”The recruits could be thrust into playing time due to the lack of depth, but none are expected to have Young’s impact. He demonstrated speed and elusiveness during his freshman season that has convinced the Buckeyes he will be a force when he steps into a starting role for Ohio State.Cooper’s name often gets lost in the shuffle — overlooked in favor of Bosa and Young — when looking ahead to 2018. Cooper did not have as much impactful playing time as Young in 2017 and had just two sacks. But the players all believe he has the chance to be another top option for the Buckeyes when they need relief.“If you name me and Nick, you’ve got to name Coop too,” Young said after the Cotton Bowl. “Coop, his motor is unreal and I don’t think guys have seen a lot of him this year, but like I said with [defensive tackle] Davon Hamilton, you going to see a lot of him next year, you going to see what he brings to the table.”Ohio State is going to have to deal with a lack of depth, but there is still plenty of talent at defensive end. With Young, Bosa and Cooper, the Buckeyes have a formidable trio that should present challenges to opposing offensive lines, just like they did in 2017.“I think it could be the best pass-rushing unit ever,” Bosa said on Jan. 19. “I think it could be a step up from last year just because they’ve really set the bar for us and we’re going to enhance it and just so much talent on this D-line right now, even though we’re young. Some of the best talent that I’ve ever seen, so it’s going to be really good once we get all the chemistry together.”
Instead, they are likely to follow in the footsteps of the Queen with hopes for a home birth, expected to be at their new home in Windsor. Read the latest updates from the London Marathon herePrince Harry has made a surprise visit to the London Marathon today, which suggests Meghan Markle is not yet due to give birth.The Duke of Sussex was seen laughing and joking as he presented medals to early Marathon finishers. The Prince also spent time talking to volunteers.He also presented medals to the marathon and wheelchair winners, including victors in the World Para Athletics World Championship Marathon.It is believed he always planned to go, but did not publicly commit to the event as it was so close to his wife’s due date.He has previously attended the event for the mental health charity Heads Together, along with the Duke and Duchess of Cambridge. Kenya’s Brigid Kosgei celebrates winning the women’s elite race with the trophy as she poses with Britain’s Prince Harry Credit: REUTERS/Paul Childs The royal baby is due soon, however, as earlier this year nine-month pregnant Meghan let slip that she is due at the end of April or early May during an engagement in Birkenhead.The couple is keeping plans for the birth private, and have said they will be “celebrating privately as a new family” after the birth as a first priority. While photographs of the baby will be taken in the following days, the family of three will not greet members of the public in the same way as the Cambridges and other members of the Royal Family have done. The palace are expected to issue a short written announcement confirming the Duchess is in labour, with a second to follow upon the safe arrival of the baby, giving details of its sex, weight and time of birth. It is understood that photographs of the baby, taken in Windsor, will be issued later, when he or she is a few days old.The couple are also likely to utilise their Sussex Royal Instagram page to share news and images of their choice. Want the best of The Telegraph direct to your email and WhatsApp? Sign up to our free twice-daily Front Page newsletter and new audio briefings.
Tweet thisShare on FacebookEmail this article Short URL Source: Shutterstock/Vinicius TupinambaEVERY WEEKDAY EVENING, TheJournal.ie brings you the five stories you need to know as you head home for the day.1. #RHONA MAHONY: The master of the national maternity hospital has said the new hospital will be entirely independent.2. #SPEEDING FINES: Those who earn more may end up paying higher speeding fines under new proposals.3. #TISSUE ISSUES: At least two people have been arrested over a ’tissue packet begging scam’ on Irish trains.4. #WALL REBOUND: Donald Trump has backed down on a funding demand for the Mexico border wall.5. #TRANSFER DEALINGS: Several arrests have been made after police raids at Newcastle United and West Ham United football clubs over suspected transfer improprieties. Share4 Tweet Email Wednesday 26 Apr 2017, 4:59 PM 12 Comments http://jrnl.ie/3359092 Apr 26th 2017, 4:59 PM 7,274 Views By Cianan Brennan The 5 at 5: Wednesday Five minutes, five stories, five o’clock…
Des cellules centenaires reprogrammées au stade de cellules souchesDes chercheurs français ont démontré que le processus de vieillissement des cellules pouvait être réversible. Ils sont parvenus à reprogrammer des cellules de donneurs âgés de 70 à plus de 100 ans en cellules souches pluripotentes, leur redonnant ainsi leur jeunesse. C’est une véritable prouesse qu’ont réalisée des chercheurs de l’Institut de génomique fonctionnelle (Inserm/CNRS/université de Montpellier). En effet, depuis des décennies, le processus de vieillissement de nos cellules fait l’objet de nombreuses études scientifiques : quels sont les mécanismes en jeu, les molécules qui interviennent, quels changements sont observés, mais aussi et surtout est-il possible d’inverser ce processus ? Or, depuis 2007, les scientifiques ont montré qu’il était possible de reprogrammer des cellules adultes humaines en cellules souches pluripotentes (iPSC pour Induced pluripotent stem cells) dont les propriétés sont similaires à celles des cellules souches embryonnaires. Autrement dit, celles-ci sont capables de se différencier en n’importe quel type de cellules de l’organisme. Cette découverte a ainsi permis de mettre au point une nouvelle technique et d’éviter les critiques sur l’utilisation de cellules souches d’embryons.Un cocktail de facteurs génétiques Toutefois, jusqu’ici, la reprogrammation de cellules adultes se heurtait à une limite : la sénescence, point ultime du vieillissement cellulaire qui se caractérise entre autres par un arrêt de la prolifération des cellules. Mais, Jean-Marc Lemaitre et ses collègues sont parvenus à franchir cette limite en reprogramment des cellules de donneurs âgés de plus de 100 ans en cellules souches pluripotentes. À lire aussiPour détecter les cellules souches cancéreuses, des chercheurs proposent de les activer artificiellementPour cela, ils ont d’abord fait multiplier des cellules de la peau d’un donneur âgé de 74 ans pour atteindre le stade de sénescence espéré. Puis ils ont procédé à la reprogrammation de ces cellules en utilisant un cocktail de six facteurs génétiques : les quatre qui étaient déjà utilisés de manière classique (OCT4, SOX2, C MYC et KLF4) plus deux autres supplémentaires (NANOG et LIN28). Au final, ils ont ainsi observé que les cellules sénescentes reprogrammées avaient réacquis les caractéristiques de cellules souches pluripotentes de type embryonnaire, ne conservant aucune trace de leur vieillissement antérieur.Une source idéale pour réparer des organes ou des tissus”Les marqueurs de l’âge des cellules ont été effacés, et les cellules souches iPSC que nous avons obtenues peuvent produire des cellules fonctionnelles, de tous types avec une capacité de prolifération et une longévité accrues”, explique Jean-Marc Lemaitre cité par l’AFP. Mais ce n’est pas tout, puisque au cours de leurs travaux publiés dans la revue Genes & Development, les chercheurs ont également confirmé ces résultats avec des cellules de donneurs plus âgés, de 92, 94, 96 et jusqu’à 101 ans. “L’âge des cellules n’est définitivement pas une barrière à la reprogrammation”, commente ainsi le chercheur de l’INSERM. Selon lui, ces travaux sur la possibilité d’effacer les marques de vieillissement des cellules marquent donc une nouvelle étape vers la médecine régénérative pour corriger une pathologie. En effet, ces cellules reprogrammées iPS pourraient être une source idéale de cellules adultes tolérées par le système immunitaire, pour réparer des organes ou des tissus chez des patients âgés. Par ailleurs, cette découverte fournit également des données supplémentaires pour mieux comprendre le vieillissement et éventuellement corriger ses aspects pathologiques. Le 1 novembre 2011 à 17:01 • Maxime Lambert
Facebook Twitter Google+LinkedInPinterestWhatsAppNassau, Bahamas, October 6, 2016 – Harrowing reports coming out of Nassau as we are told that people in coastal areas are now crying for rescues, but that cannot happen and it means these individuals will have to figure out how to survive the onslaught of now category four hurricane Matthew with its 140 mph winds. “We have reports of many people saying, oh come, homes have been compromised, the roofs blowing off or part of the roofs blowing off, and that sort of thing, and due to the high winds, medical rescue and teams were asked not to take the risk. The broad surge to all of the southern shores, I’m only getting reports from Yamacraw, Marshal Road, Harold Road, those roads in the south eastern end of New Providence, that’s where we getting calls coming in right now.” Trevor Basden There are images of vehicles submerged in the Yamacraw area; there is a nearby beach which has caused an at least 5ft tall surge to rush in. Basden explains, that it is not rain, it is a storm surge which has drowned vehicles and homes; even toppled the wall at Fox Hill Prison.“Fox Hill Prison, the wall on Yamacraw side, the entire wall of Fox Hill Prison is down, it’s completely washed away.” Related Items:calls for rescue ring out in new providence, cars submerged in water in nassau, hurricane matthews rips through new providence, massive flooding in areas of nassau The best news which we hope holds up as the Bahamas is bashed by Matthew; there there are no reports of loss of life. Trevor Basden is the Sr Deputy Director of the Bahamas Department of Meteorology and he said Nassau has up until 3 p.m with the hurricane force winds, and Grand Bahama will experience Hurricane conditions until 7 a.m tomorrow. That gives killer storm Matthew lots of time to do the dastardly to the island which is still reeling from the hits of Frances and Jeanne in 2004 and Wilma in 2005. Winds are described in Nassau as violent. Winds are described in Grand Bahama as picking up. The storm veering more west, on a collision course with West End by all appearances. In the west an evacuation order was given; some but not all heeded the request. And at best, official rescue operations will not be permitted in Nassau said Mr. Basden until after 3pm and even then the first responders are going out in Tropical Storm force winds which are risky. “How y’all holding up in this weather man, I’m talking about this weather so strong, it shake my bed; in my house.” – Cody (resident) Many lost power last night, some this morning and the images of disaster are many… the bridge, businesses, hotels, homes, water ways and historic buildings – all abused by the unrelenting Matthew which has killed hundreds; the death toll from Haiti today soars to 108. A knight on a huge truck trying to plow through six feet of water he says, to get a family to safey… we pray they make it okay. NEMA is also receiving reports of roofs flying off and we have gotten a report of doors of homes flying off. There is also, likely an unauthorized expedition to save those who are stuck – remember evacuation recommendations were made for many areas in Nassau. “I am in a dump truck right now and we are in six feet of water, South Beach when I say is under water, we are trying to locate some people who are trapped in their ceilings.” – (rescue crew member) Facebook Twitter Google+LinkedInPinterestWhatsApp
DLF logoWikimedia CommonsReal estate giant DLF has repaid Rs 3100 crore of debt to its venture partner GIC by transferring Noida shopping mall and some land parcels. DLF owed about Rs 8,700 crore to DLF Cyber City Developers LTD (DCCDL), which is a joint venture between DLF and Singapore sovereign wealth fund GIC. With the latest transaction, DLF’s debt has come down to about Rs 5600 crore as of July 2019.In an investor presentation, DLF clarified that it has transferred the Mall of India project in Noida, worth Rs 2950 crore, to DCCDL. The Economic Times also reported that the company also added that it has transferred 3.05 acres of land parcel in Gurugram to the Singapore-based firm. Representational ImageINDRANIL MUKHERJEE/AFP/Getty ImagesThe joint venture between GIC and DLF was signed in December 2017 when DLF promoters sold 40 percent of their stake in DCCDL to GIC for about Rs 1,200 crore. The deal included the sale of DCCDL’s 33.34 percent stake to GIC for about Rs 9,000 crore and the remaining Rs 3m000 crore was acquired by DCCDL through buyback.DLF holds about 66.66 percent in the joint venture firm and the remaining 33.34 percent is with GIC. The Gurgaon-based real estate giant has plans to sell prime commercial project Horizon Central in Gurugram for about Rs 850 crore, to settle the remaining debt of Rs 5,600 crore. The company also plans to transfer its mall in Saket for a valuation of Rs 1,050 crore, reported ET. Real estateThe report also stated that DLF will transfer its commercial land in Chennai for about Rs 1,000 crore. Some parts of the monetary settlement to GIC will be done by transferring SEZs at Hyderabad and Chennai as per the contract with group firm DLF Assets Ltd. The leftover debt of about Rs 7,00 will be paid in cash.DLF has reported a two-fold growth in its profit at Rs 414.72 crore for the June quarter against Rs 172.77 crore last year. DCCDL holds about 30 million sqft of commercial real estate in Gurugram that yields an annual revenue of about Rs 3,000 crore.
Hydrogen-Powered Plane Can Fly 20 Passengers Up to 500 MilesAirbnb For Work Simplifies Business Travel Stay on target If you’re looking for a spooky Halloween destination, book a flight to Mexico ASAP. Located in the canals of Xochimilco, Isla de las Muñecas (Island of the Dolls) is home to thousands of creepy dolls with severed limbs and decapitated heads hanging from trees and littered in the cabins. Many of the decaying, insect-infested dolls have been hanging for 15 years, transforming the island into a sort of bizarre (some say haunted) doll-wonderland.According to locals, a former caretaker of the island named Don Julian Santana Barrera collected and hung up the dolls to honor the life of a young girl who drowned in the area. Don Julian was apparently “haunted by the spirit of the girl and started hanging more dolls in an attempt to please her spirit,” a website for the island states. Don Julian died in 2001, and his family now run the area as tourist attraction (the island is accessible via boat) where visitors hang other dolls and claim to hear them whispering or moving.Click through the slideshow to see images from the Island of the Dolls.View as: One Page Slides1/131. Isla de las Munecas (Island of the Dolls) in Xochimilco, MexicoPhoto Credit: Sebastian Perez Lira/Barcroft/Barcroft Media via Getty ImagesOne of Mexico’s creepiest tourist attractions, Isla de las Muñecas (Island of the Dolls) is located in the channels of Xochimilco. The island is home to thousands of spooky dolls hanging from trees, and is said to be dedicated to a girl who drowned and died in the area.2. Isla de las Munecas (Island of the Dolls) in Xochimilco, MexicoPhoto Credit: Sebastian Perez Lira/Barcroft/Barcroft Media via Getty ImagesOne of Mexico’s creepiest tourist attractions, Isla de las Muñecas (Island of the Dolls) is located in the channels of Xochimilco. The island is home to thousands of spooky dolls hanging from trees, and is said to be dedicated to a girl who drowned and died in the area.3. Isla de las Munecas (Island of the Dolls) in Xochimilco, MexicoPhoto Credit: Sebastian Perez Lira/Barcroft/Barcroft Media via Getty ImagesOne of Mexico’s creepiest tourist attractions, Isla de las Muñecas (Island of the Dolls) is located in the channels of Xochimilco. The island is home to thousands of spooky dolls hanging from trees, and is said to be dedicated to a girl who drowned and died in the area.4. Isla de las Munecas (Island of the Dolls) in Xochimilco, MexicoPhoto Credit: Sebastian Perez Lira/Barcroft/Barcroft Media via Getty ImagesOne of Mexico’s creepiest tourist attractions, Isla de las Muñecas (Island of the Dolls) is located in the channels of Xochimilco. The island is home to thousands of spooky dolls hanging from trees, and is said to be dedicated to a girl who drowned and died in the area.5. Isla de las Munecas (Island of the Dolls) in Xochimilco, MexicoPhoto Credit: Sebastian Perez Lira/Barcroft/Barcroft Media via Getty ImagesOne of Mexico’s creepiest tourist attractions, Isla de las Muñecas (Island of the Dolls) is located in the channels of Xochimilco. The island is home to thousands of spooky dolls hanging from trees, and is said to be dedicated to a girl who drowned and died in the area.6. Isla de las Munecas (Island of the Dolls) in Xochimilco, MexicoPhoto Credit: Sebastian Perez Lira/Barcroft/Barcroft Media via Getty ImagesOne of Mexico’s creepiest tourist attractions, Isla de las Muñecas (Island of the Dolls) is located in the channels of Xochimilco. The island is home to thousands of spooky dolls hanging from trees, and is said to be dedicated to a girl who drowned and died in the area.7. Isla de las Munecas (Island of the Dolls) in Xochimilco, MexicoPhoto Credit: Sebastian Perez Lira/Barcroft/Barcroft Media via Getty ImagesOne of Mexico’s creepiest tourist attractions, Isla de las Muñecas (Island of the Dolls) is located in the channels of Xochimilco. The island is home to thousands of spooky dolls hanging from trees, and is said to be dedicated to a girl who drowned and died in the area.8. Isla de las Munecas (Island of the Dolls) in Xochimilco, MexicoPhoto Credit: Sebastian Perez Lira/Barcroft/Barcroft Media via Getty ImagesOne of Mexico’s creepiest tourist attractions, Isla de las Muñecas (Island of the Dolls) is located in the channels of Xochimilco. The island is home to thousands of spooky dolls hanging from trees, and is said to be dedicated to a girl who drowned and died in the area.9. Isla de las Munecas (Island of the Dolls) in Xochimilco, MexicoPhoto Credit: Sebastian Perez Lira/Barcroft/Barcroft Media via Getty ImagesOne of Mexico’s creepiest tourist attractions, Isla de las Muñecas (Island of the Dolls) is located in the channels of Xochimilco. The island is home to thousands of spooky dolls hanging from trees, and is said to be dedicated to a girl who drowned and died in the area.10. Isla de las Munecas (Island of the Dolls) in Xochimilco, MexicoPhoto Credit: Sebastian Perez Lira/Barcroft/Barcroft Media via Getty ImagesOne of Mexico’s creepiest tourist attractions, Isla de las Muñecas (Island of the Dolls) is located in the channels of Xochimilco. The island is home to thousands of spooky dolls hanging from trees, and is said to be dedicated to a girl who drowned and died in the area.11. Isla de las Munecas (Island of the Dolls) in Xochimilco, MexicoPhoto Credit: Sebastian Perez Lira/Barcroft/Barcroft Media via Getty ImagesOne of Mexico’s creepiest tourist attractions, Isla de las Muñecas (Island of the Dolls) is located in the channels of Xochimilco. The island is home to thousands of spooky dolls hanging from trees, and is said to be dedicated to a girl who drowned and died in the area.12. Isla de las Munecas (Island of the Dolls) in Xochimilco, MexicoPhoto Credit: Sebastian Perez Lira/Barcroft/Barcroft Media via Getty ImagesOne of Mexico’s creepiest tourist attractions, Isla de las Muñecas (Island of the Dolls) is located in the channels of Xochimilco. The island is home to thousands of spooky dolls hanging from trees, and is said to be dedicated to a girl who drowned and died in the area.13. Isla de las Munecas (Island of the Dolls) in Xochimilco, MexicoPhoto Credit: Sebastian Perez Lira/Barcroft/Barcroft Media via Getty ImagesOne of Mexico’s creepiest tourist attractions, Isla de las Muñecas (Island of the Dolls) is located in the channels of Xochimilco. The island is home to thousands of spooky dolls hanging from trees, and is said to be dedicated to a girl who drowned and died in the area.More on Geek.com:Photos: Eerie Ghost Towns to Visit (If You Dare)Photos: Abandoned Water Park is Straight Out of a Horror Film7 Horror Movies You Forgot Were Great
Of other Arizona representation for the apparel company, Matt Williams’ Arizona Diamondbacks jersey and two colors each of Steve Nash’s and Kevin Johnson’s Phoenix Suns jerseys are for sale.Los Angeles Lakers legend Kobe Bryant, who last night played his final game against the Phoenix Suns before his retirement, had the best-selling jersey in California, Oregon and Ohio and was the top-selling retro jersey for the company overall. Boston Celtics star Larry Bird had the best-selling jersey in the most states (4). Those who have resided in Arizona for a long time and natives of the Grand Canyon State especially won’t find this surprising. Sports apparel store Mitchell & Ness released their state-by-state list of the best-selling retro jerseys of 2015, and for Arizona, the late Pat Tillman had the most popular jersey for the second year in a row.Mitchell & Ness sells three different versions of Tillman’s No. 40 Arizona Cardinals jersey. The 5: Takeaways from the Coyotes’ introduction of Alex Meruelo Grace expects Greinke trade to have emotional impact Derrick Hall satisfied with D-backs’ buying and selling 0 Comments Share Mitchell & Ness Former Cardinals kicker Phil Dawson retires Top Stories
Ort: St.Anton am Arlberg (Region)Go back to the e-newsletterThose heading out on the slopes in St Anton am Arlberg in winter 2016/17 will find themselves in the largest interlinked ski area in Austria, with 305 kilometres of marked ski runs and 87 lift and cable car systems. Thanks to the new Flexenbahn lift between Stuben/Rauz and Zürs, winter sports enthusiasts will be able to explore the entire Arlberg area, known as ‘the cradle of alpine skiing’.The full dimensions of this interlinked ski region can be best experienced along the “Run of Fame”. With 65 kilometres of runs and 18,000 metres in altitude difference, this new ski circuit leads through the entire Arlberg ski area.The Ski Arlberg common tariff system has been in place for many years, although the ski connection between Tyrolean St Anton and Zürs in Vorarlberg was previously only possible by road. When building of the 1.8-kilometre-long Flexenbahn and the two Trittkopfbahnen lifts commences in spring 2016, winter sports enthusiasts will be able to take advantage of an integrated ski infrastructure between the two world famous ski resorts.Thanks to the equally new Albonabahn II, the northern slopes of Albona will be more quickly accessible in future. Instead of starting from Stuben, powder fans can set off from Alpe Rauz.These connections give rise to a spectacular ski circuit: with 65 kilometres of runs and 18,000 metres in altitude difference, the “Run of Fame” leads through the entire Arlberg ski area. Even the most proficient skier will need a whole day to ski from the southernmost point in St Anton/Rendl to Warth in the north and back again. The circuit can be accessed from almost anywhere and “Run of Fame” info-points and signposts will be installed. “Run of Fame” stars will also remind skiers of Arlberg’s greatest ski legends – as the track is dedicated to sporting stars such as Hannes Schneider, Karl Schranz and Mario Matt.Go back to the e-newsletter
Las Vegas, Nevada – Reported by Elite Traveler, the Private Jet Lifestyle MagazineMandarin Oriental, Las Vegas has been named one of the newest recipients of the esteemed AAA Five Diamond Award rating and the coveted Forbes Five-Star award for its Spa. These prestigious accolades reflect Mandarin Oriental, Las Vegas’ dedication to creating an outstanding experience for all guests. Since its doors opened in December 2009, this chic, sophisticated hotel and residences has received multiple accolades for its impeccable accommodations and amenities, its holistic spa and innovative dining options.“Mandarin Oriental, Las Vegas is deeply honored to have received this recognition,” said Rajesh Jhingon, General Manager of the property. “This is a testimony to the fantastic and engaged service that we strive to deliver day after day.”The AAA Five Diamond Award designation for hotels and restaurants is among North America’s most coveted symbols of excellence in the hospitality industry. Representing the upper echelon of the hospitality industry, AAA Five Diamond Award winners make up less than one-half percent of more than 31,000 AAA Approved properties throughout the United States, Canada, Mexico and the Caribbean. AAA defines Five Diamond properties as establishments with first-class accommodations and reflecting the ultimate characteristics in luxury and sophistication. Exceeding guest expectations, providing meticulous service and maintaining impeccable standards of excellence are the fundamental hallmarks of the AAA Five Diamond rating.Forbes Travel Guide’s (formerly Mobil Travel Guide) Star Awards ratings process is based on more than 750 standardized criteria for hotels, restaurants and spas worldwide, making it the most rigorous and comprehensive in the industry. To achieve Forbes Travel Guide Four and Five Star status, properties must meet or exceed the bar-setting service standards, which are determined through an unannounced, undercover service evaluation conducted by Forbes Travel Guide’s expert inspectors.www.mandarinoriental.com/lasvegas
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